The Orb of Alchemy in Path of Exile 2 has a moderate drop rate, making it relatively accessible but still valuable for crafting. It can drop from various sources including monsters, chests, and strongboxes, with increased chances in higher difficulty levels such as Cruel difficulty and beyond. Early in the game, the drop rate is somewhat lower but improves as players progress to mid and endgame areas where monster density and loot quality increase. For many players, managing this alongside other poe 2 currency becomes a core part of sustainable progression.

Specific rare enemies in Act 2, like Lim the Impaler and Ninth Treasure of Keth, are popular targets for farming Orbs of Alchemy due to their guaranteed rare status and higher drop chances in Cruel difficulty. Players can repeatedly defeat such enemies and use corpse-destroying skills combined with checkpoint reloads to optimize orb farming. This method is efficient because it exploits the game mechanics to maximize orb drops in a short time.

Orbs of Alchemy also drop from Arcanist’s Strongboxes and rare containers found in maps and endgame content. In general, map farming and delves with dense monster packs provide consistent orb drop opportunities, with higher levels offering better quantities. Event participation and vendor recipes targeting rare items with particular affixes can also supplement orb farming.

The drop rate of Orbs of Alchemy has been buffed in POE 2 compared to its predecessor to support smooth gear progression through the game's acts. This improvement helps players upgrade their equipment steadily without excessive grinding. Though exact numeric drop rates are not public, the community consensus is that orbs drop regularly enough during normal gameplay, making them reliable but still rewarding currency to obtain. For players aiming to craft faster and reduce grind time, some choose to poe 2 currency for sale through trading communities or player markets.

In terms of efficiency, players should farm areas with high monster density and quick boss or rare monster kills to maximize their orb haul. Utilizing recurrent farming spots and checkpoint resets for special enemies can significantly boost orb acquisition rates. Balancing farming efficiency with gameplay enjoyment and exploration ensures a sustainable supply of Orbs of Alchemy for continuous crafting needs throughout POE 2’s progression.

By focusing farming efforts on specific zones, rare enemies, strongboxes, and endgame maps, players can maintain an efficient flow of Orbs of Alchemy. This ensures they have the necessary currency for crafting powerful rare gear upgrades without delay, supporting both leveling and endgame build optimization.